Summary:The minispec Body Composition Analyzer is based on Time Domain NMR. It acquires and analyzes TD-NMR signals from all protons in the entire sample volume and can provide 3 components of interest: Fat, Free Body Fluid and Lean Tissue values. Bruker's minispec Body Composition Analyzer provides a precise method for measurement of lean tissue, fat and fluid in living mice. TD-NMR uses NMR technology, providing analysis of fat tissue, lean tissue and free fluid by the same physical selection rules that give rise to contrast in MRI. Tissue contrast is high between fat and muscle based on relative relaxation times. This Magnetic Resonance technology provides our users with the opportunity to make multiple measurements during the life of the animal with the following benefits: ♦ Rapid analysis: measurement takes less than 2 minutes, no sample preparation ♦ Economical procedures: no consumables, retain expensive lab animals for entire study ♦ Reduced animal stress: no need for anesthetics; animals are measured "as-is" ♦ Allows more frequent testing, due to reduction of risks to animal health ♦ Better accuracy and precision compared to DEXA (X-ray) method