Summary:\nVertical sleeve Gastrectomy (VSG) is a common surgical treatment of obesity, type-2 diabetes, and other comorbidities of obesity. The VSG mouse surgical model provides researchers with a mechanism to evaluate mechanistic studies to explore the methods by which VSG bariatric surgery produces beneficial effects on obesity. The surgical procedure is performed under sterile conditions in accordance with AAALAC standards. Surgical animals will be able to ship 2 weeks after the post-operative monitoring period is completed. Cohorts of Vertical Sleeve gastrectomy (VSG), a pair fed SHAM, and an ad lib SHAM will be provided with each cohort ordered.