Jun 04, 2026

Photobiomodulation for genitourinary syndrome of menopause

DOI
https://dx.doi.org/10.17504/protocols.io.eq2lyokqegx9/v1
  • Pei-Chi Wu1
  • 1National Taiwan University Hospital
  • National Taiwan University Hospital
Pei-Chi Wu
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DOI: https://dx.doi.org/10.17504/protocols.io.eq2lyokqegx9/v1
Protocol Citation: Pei-Chi Wu 2026. Photobiomodulation for genitourinary syndrome of menopause. protocols.io https://dx.doi.org/10.17504/protocols.io.eq2lyokqegx9/v1
License: This is an open access  protocol  distributed under the terms of the  Creative Commons Attribution License,  which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited
Protocol status: Working
We use this protocol and it's working
Created: May 07, 2026
Last Modified: June 04, 2026
Protocol  Integer ID: 316595
Keywords: photobiomodulation for genitourinary syndrome, prospective evaluation of photobiomodulation, menopause protocol for the clinical trial, menopause protocol, photobiomodulation, genitourinary syndrome, clinical trial
Funders Acknowledgements:
National Taiwan University Hospital
Grant ID: 113-N0021
Abstract
Protocol for the clinical trial: Prospective evaluation of photobiomodulation for genitourinary syndrome of menopause
ClinicalTrials.gov: NCT06074120.
Device Information
Manufacturer / Model: Transverse Industries Co., Ltd, Taiwan — TI-816-12
Emitter type: AlGaInP semiconductor diode laser
Number of emitters: Single
Spatial distribution of emitters: Single emitter at probe center
Beam delivery system: Silicone light guide vaginal probe
Beam / Irradiation Parameters
Center wavelength: 660 nm
Spectral bandwidth: ±10nm
Operating mode: Pulsed
Frequency: 20 Hz
Pulse on duration: 0.025 sec
Duty cycle: 50%
Energy per pulse: 0.0184 J
Polarization: Linear
Aperture diameter: 1.2 cm
Irradiance at aperture: 646.99 mW/cm²
Beam divergence: ≈0.35 mrad
Beam shape: Circular
Beam profile: Uniform
Treatment Dosimetry
Peak radiant power: 737.57 mW
Average radiant power: 368.79 mW
Beam spot size at target: 2 cm²
Irradiance at target: Tip of probe: 32.38 mW/cm², Side of probe: 13.38 mW/cm²
Exposure duration: 1800 sec (30 min per session)
Radiant exposure (Fluence): Vaginal fornix: 29.14 J/cm², Vaginal wall: 12.04 J/cm²
Radiant energy (per session): 178.7 J
Number of points irradiated: Whole vaginal mucosa
Area irradiated: 12cm²
Application technique: Contact
Number of sessions: 8 sessions
Total radiant energy: 1429.6 J