Nov 25, 2020
Performance Study of Wireless Fecobionics Device in Canine
- Yanmin Wang1,
- Hans Gregersen1
- 1California Medical Innovations Institute
Protocol Citation: Yanmin Wang, Hans Gregersen 2020. Performance Study of Wireless Fecobionics Device in Canine. protocols.io https://dx.doi.org/10.17504/protocols.io.bpzfmp3n
License: This is an open access protocol distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited
Protocol status: Working
We use this protocol and it's working
Created: November 23, 2020
Last Modified: November 25, 2020
Protocol Integer ID: 44807
Keywords: Colon, bionics, cannula, colonoscopy, fluoroscopy,
Abstract
We developed a novel wireless device (Fecobionics) for mapping colonic and anorectal neuromuscular function. The hypothesis of this protocol is that the Fecobionics device can test pressures, orientation, bending, shape, and cross-sectional area changes in colon and rectum. To validate our hypothesis, we inserted the device to the proximal colon, either through a cannula or colonoscopy, followed by data transmission and recording.
Cannula test
Cannula test
After a laparotomy, a cannula was implanted into the proximal of the colon (4-5 cm to cecum)
The external end of the cannula was screwed by a cap, which is able to open for device insertion
After 10-14 days recovery, the Fecobionics was inserted through the cannula for testing
X-ray fluoroscopy was performed frequently to locate the device. Data was recorded for analysis.
Colonoscopy
Colonoscopy
After 2-day laxative and an enema, the animal was anesthetize for colonoscopy
The Fecobionics was delivered to proximal colon (close to cecum) by an endoscopic rat-tooth forcep
After the delivery, X-ray fluoroscopy was performed frequently to locate the device. Data was recorded for analysis.