Jan 03, 2024
Percutaneous myocardial infarction model in rabbit
- Eline Huethorst1,
- Michael Freeman1,
- Erin Boland1,
- Michael Dunne1,
- Francis Burton1,
- Chris Denning2,
- Rachel Myles1,
- Godfrey Smith1
- 1University of Glasgow;
- 2University of Nottingham
External link: https://doi.org/10.1152/ajpheart.00657.2023
Protocol Citation: Eline Huethorst, Michael Freeman, Erin Boland, Michael Dunne, Francis Burton, Chris Denning, Rachel Myles, Godfrey Smith 2024. Percutaneous myocardial infarction model in rabbit. protocols.io https://dx.doi.org/10.17504/protocols.io.yxmvm3b39l3p/v1
Manuscript citation:
Freeman M, Huethorst E, Boland E, Dunne M, Burton F, Denning C, Myles R, Smith G (2024) A novel method for the percutaneous induction of myocardial infarction by occlusion of small coronary arteries in the rabbit. American Journal of Physiology - Heart and Circulatory Physiology 326(3). doi: 10.1152/ajpheart.00657.2023
License: This is an open access protocol distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited
Protocol status: Working
Video files to support the published research protocol.
Created: December 14, 2023
Last Modified: January 03, 2024
Protocol Integer ID: 92312
Keywords: Myocardial infarction, percutaneous surgery, intra-coronary occlusion, cardiovascular disease, closed-chest model.
Abstract
This video file contains fluoroscopic recordings of 6 steps of the percutaneous inductions of myocardial infarction in rabbit.
1. Identification of the aortic structures.
2. Insertion of the guide wire.
3. Guidance of 4F catheter over guide wire.
4. Identification of the coronary ostium and apical artery.
5. Engagement of the coronary vessel with a floppy guide wire.
6. Advancement of the micro-catheter and tip over the wire to deploy the tip.
Materials
Fluorscopic videos of various procedural steps.mp413.4MB