Aug 28, 2022
Operation of Software for Motion Correction of Cardiac MRI by Respiratory Phase
- Steven Van Doren1,
- Jia Xu2,
- Zhijian Luan2,
- Afia Shammi2
- 1Biochemistry Dept., Institute for Data Science and Informatics, University of Missouri, Columbia, Missouri, United States;
- 2University of Missouri, Columbia, Missouri, United States
Protocol Citation: Steven Van Doren, Jia Xu, Zhijian Luan, Afia Shammi 2022. Operation of Software for Motion Correction of Cardiac MRI by Respiratory Phase. protocols.io https://dx.doi.org/10.17504/protocols.io.36wgq72j5vk5/v1
Manuscript citation:
Shammi AU, Luan Z, Xu J, Hamid A, Flors-Blasco L, Cassani J, Altes T, Thomen RP, Van Doren SR. Simplification of Free-Running Cardiac Magnetic Resonance by Respiratory Phase. Submitted to PLoS One. Manuscript ID# PONE-D-22-14289
License: This is an open access protocol distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited
Protocol status: Working
We use this protocol. It works fine on real-time scans from a Siemens MRI scanner.
Created: August 15, 2022
Last Modified: August 28, 2022
Protocol Integer ID: 68666
Keywords: real-time cardiac MRI, free-breathing MRI, motion correction, compressed sensing, post-processing, principal component analysis, Windows operating system, time cardiac mri scans during breathing, breathing motion in such scan, motion correction of cardiac mri, cardiac mri scan, heart contraction during the dynamic scan, cardiac mri, breathing motion, cardiac cycle, cardiac cycles at end, cardiac cycles from end, time courses of breathing, other with the cardiac cycle, heart contraction, respiratory phase collection, breathing, dynamic scan, motion correction, scan, software under window, such scan, breath, software, dicom file
Funders Acknowledgements:
Coulter Translational Partnership Program at the University of Missour
Grant ID: HeartSpeed for Free-breathing Cardiac MRIs
Abstract
Collection of real-time cardiac MRI scans during breathing is desirable for sick patients unable to hold their breath. The breathing motion in such scans can, however, can be distracting for physicians and clinical staff. Here we introduce the simple operation of our software that minimizes distracting breathing motion in a cardiac MRI scan. The software segregates the cardiac cycles at end-expiration and end-inspiration. The software generates two DICOM files: one with the cardiac cycles from end-expiration (recommended) and the other with the cardiac cycles from end-inspiration (use as needed). The software also plots the time courses of breathing and heart contraction during the dynamic scan, providing a temporal "road map" of the scan. Only a few clicks are needed to operate the software under Windows.
Materials
We acquired the images using a Siemens 3T Magnetom VIDA; Syngo MR XA20 with dedicated phased-array cardiac receiver coils (18-channel chest coil, 32-channel spine coil). Patients were placed in the supine position and the chest coil was placed by a MR tech. Free breathing images were acquired with conventional bSSFP and compressed sensing bypassing electrocardiographic (ECG) triggering. The commercial compressed sensing package allowed us to acquire images up to 22 frames/sec.
Troubleshooting
Before start
The real-time cardiac MRI scan should be collected throughout at least a full breath out and in, and preferably through multiple respiratory cycles.
The image quality of heart beats during breaths out is highest. Deep breaths in decreased the quality of those image frames in our study. Asking the subject to take only shallow breaths in could improve the image quality of the cardiac cycles during inspiration.
This software is intended to be vendor-neutral and neutral to the type of real-time acquisition. However, we have only tested this software on cardiac CMR scans acquired with a Siemens system with the cardiac compressed sensing option installed. We invite user feedback regarding usages with scans from other scanners and other acquisition strategies.
Software setup
Install the software
Request licensing and price (academic or commercial) by corresponding author Steven Van Doren ([email protected] ) and/or the Technology Transfer Office of the University of Missouri ([email protected]).
Copy the software package (a zip file) to a hard drive, such as the C: drive
Run the software
Double click the MoCo icon to launch the software.
Click on the Motion Correction tab.
Select import dcm to import a scan in DICOM format.
Choose the CMR scan in DICOM format to import.
Now the software will run automatically. 00:05:00 It will show the time courses of breathing and heart contraction. After noting these time courses, close this window so that the program can continue to run.
5m
A message box will pop up when the task is completed. Click on the OK button.
A folder with the results will pop up automatically. The following files will be produced:
- Inspiratory DICOM file: It includes all the heart beats during inspiration (e.g, Subj_2_MRI_insp)
- Expiratory DICOM file: It includes all the heart beats during expiration (e.g, Subj_2_MRI_exp)
- Excel spread sheet: This includes all the principal components in a spreadsheet.
Exit & View
Exit the program by clicking “Exit”.
Read at least the cardiac cycles from expiration into a DICOM viewer.
Software
ImageJ/Fiji
NAME
Windows 7
OS
National Institutes of Health
DEVELOPER
SOURCE LINK