Step 6 — Collating, Summarizing, and Reporting
Extracted data will be collated and synthesized to summarize the evidence on the associations between the dimensions of the MESSi (morning affect, eveningness, and distinctness) and mental health outcomes. Study characteristics will be summarized in structured evidence tables. Findings will be organized according to MESSi dimensions and categories of mental health outcomes. Moreover, a narrative synthesis will be conducted to describe the direction and strength of associations across the included studies.
The methodological quality and risk of bias of the included studies will be independently assessed by two reviewers. The specific appraisal tools will be selected according to the study design of the included articles. Discrepancies between reviewers will be resolved through discussion, and if necessary, by consultation with a third reviewer.
If at least five studies report sufficiently comparable statistical data for the same MESSi dimension and mental health outcome, a quantitative synthesis (meta-analysis) will be conducted. In such cases, pooled effect sizes will be calculated and statistical heterogeneity will be assessed. If fewer than five comparable studies are identified, results will be summarized descriptively.
Preferred Reporting Items for Systematic reviews and Meta-Analyses will be applied:
Page, M. J., Moher, D., Bossuyt, P. M., Boutron, I., Hoffmann, T. C., Mulrow, C. D., ... & McKenzie, J. E. (2021). PRISMA 2020 explanation and elaboration: updated guidance and exemplars for reporting systematic reviews. bmj, 372.