License: This is an open access collection distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited
Protocol status: Working
Collection for Spatial Profiling of FFPE mouse brain tissue
Created: August 28, 2025
Last Modified: August 28, 2025
Collection Integer ID: 225670
Keywords: aging, microglia, white matter, neuroinflammation, senescence, microglia in aged mouse brain white matter, aged brain spatial profiling collection, aged mouse brain white matter, associated microglia, microglia, mice brain tissue, digital spatial profiling cosmx, protocols for brain tissue, processing immunofluorescence imaging geomx, case selection for mice brain tissue, spatial molecular imaging, brain tissue, protocol methodology doi for brain imaging, brain imaging, senolytic targeting of senescent, senolytic targeting, spatial
Funders Acknowledgements:
NIH Cellular Senescence Network
Grant ID: UG3 CA275669
National Institute on Aging
Grant ID: R00 AG05879
National Institute on Aging
Grant ID: R01 AG071686
Abstract
This collection contains to the protocol methodology DOI for brain imaging produced in Carver et al., "Spatial
mapping and senolytic targeting of senescent and disease-associated microglia in aged mouse brain white matter".
