Aug 08, 2024

KAPP-Sen TMC: Pancreas Donor Acceptance Criteria V.2

DOI
https://dx.doi.org/10.17504/protocols.io.j8nlkokddv5r/v2
  • Cristina Aguayo-Mazzucato1,
  • Kanako Iwasaki1,2
  • 1Joslin Diabetes Center, Harvard Medical School, Boston, MA, USA;
  • 2Tazuke Kofukai Medical Research Institute, Kitano Hospital, Osaka, Japan
  • Cellular Senescence Network (SenNet) Method Development Community
  • KAPP-Sen TMC
Sergii Domanskyi
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DOI: https://dx.doi.org/10.17504/protocols.io.j8nlkokddv5r/v2
Protocol Citation: Cristina Aguayo-Mazzucato, Kanako Iwasaki 2024. KAPP-Sen TMC: Pancreas Donor Acceptance Criteria. protocols.io https://dx.doi.org/10.17504/protocols.io.j8nlkokddv5r/v2Version created by Sergii Domanskyi
License: This is an open access  protocol  distributed under the terms of the  Creative Commons Attribution License,  which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited
Protocol status: Working
We use this protocol and it's working
Created: August 08, 2024
Last Modified: August 08, 2024
Protocol  Integer ID: 104986
Keywords: SenNet KAPP-Sen TMC, Case selection, kapp, sen tmc
Funders Acknowledgements:
National Institute on Aging (NIA) KAPP-Sen Tissue Mapping Collaborative
Grant ID: U54 AG075941
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Abstract
Pancreas Donor Acceptance Criteria
Inclusion Criteria
  • Both sexes
  • Age > 18 years
  • All ethnicities
Exclusion Criteria
  • HTN with end-organ damage
  • BMI > 35
  • GFR < 60 ml/min/1.73 m2
  • Known cardiovascular disease
  • Pancreatitis
  • Active malignancy
  • Chronic pulmonary, hepatic, infectious, gastrointestinal, endocrine, neurologic, or inflammatory disease
  • Chronic use of systemic steroids
  • Use of agents with senolytic activity