Jul 08, 2025

Public workspaceEffect of Stretching (FNS) and Strengthening Exercise (WBE) for Diabetic Neuropathy V.1

  • MEHEDI HASAN BADSHA1,
  • Dr. Md. Feroz Kabir1
  • 1Department of Physiotherapy & Rehabilitation, Jashore University of Science & Technology
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Protocol CitationMEHEDI HASAN BADSHA, Dr. Md. Feroz Kabir 2025. Effect of Stretching (FNS) and Strengthening Exercise (WBE) for Diabetic Neuropathy. protocols.io https://dx.doi.org/10.17504/protocols.io.n2bvjernpgk5/v1
License: This is an open access protocol distributed under the terms of the Creative Commons Attribution License,  which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited
Protocol status: Working
We use this protocol and it's working
Created: July 08, 2025
Last Modified: July 08, 2025
Protocol Integer ID: 221939
Keywords: Diabetic Neuropathy, Functional Neural Stretching, Weight-Bearing Exercise, Physiotherapy., exercises into diabetic neuropathy rehabilitation protocol, diabetic neuropathy rehabilitation protocol, diabetic neuropathy, effectiveness of functional neural stretching, receiving neural stretching, neural stretching, functional neural stretching, strengthening exercise, significant improvements in pain relief, physiotherapy, stretching, structured physiotherapy protocol, standard physiotherapy, rehabilitation, neuropathy symptom, based exercise, pain relief, including pain
Funders Acknowledgements:
Department of Physiotherapy & Rehabilitation, Jashore University of Science & Technology
Abstract
This randomized controlled trial evaluates the effectiveness of functional neural stretching combined with weight-bearing exercise in managing diabetic neuropathy. The structured physiotherapy protocol aims to reduce pain and neuropathy symptoms, while enhancing functional mobility and quality of life.
The study involves 100 participants randomly assigned to either an experimental group (receiving neural stretching and weight-bearing exercise) or a control group (standard physiotherapy). Over 8 weeks, outcomes including pain, sensation, neuropathy symptoms, functional status, and quality of life will be measured.
Expected results include significant improvements in pain relief, symptom reduction, and enhanced physical function in the experimental group. These findings may support integrating targeted neurodynamic and load-based exercises into diabetic neuropathy rehabilitation protocols.
Materials
Primary Outcome Tools:
• Pain: Visual Analog Scale (VAS)
• Neuropathy Symptoms: Michigan Neuropathy Screening Instrument (MNSI)
• Ankle ROM: Goniometer
Secondary Outcome Tools:
• Mobility: Timed Up and Go (TUG) Test
• Strength: Manual Muscle Testing (MMT), WHOQOL: World Health Organization Quality of Life assessment.
Troubleshooting
Protocol references
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Callaghan, B. C., Cheng, H. T., Stables, C. L., Smith, A. L., & Feldman, E. L. (2012). Diabetic neuropathy: clinical manifestations and current treatments. The Lancet Neurology, 11(6), 521–534. https://doi.org/10.1016/s1474-4422(12)70065-0
Sartor, C. D., Hasue, R. H., Cacciari, L. P., Butugan, M. K., Watari, R., Pássaro, A. C., Giacomozzi, C., & Sacco, I. C. (2014). Effects of strengthening, stretching and functional training on foot function in patients with diabetic neuropathy: results of a randomized controlled trial. BMC Musculoskeletal Disorders, 15(1). https://doi.org/10.1186/1471-2474-15-137
Zhu, G., Chen, Y., Tsai, K., Wang, J., Hung, C., & Schmid, A. B. (2022). Effects of neural mobilization on sensory dysfunction and peripheral nerve degeneration in rats with painful diabetic neuropathy. Physical Therapy, 102(10). https://doi.org/10.1093/ptj/pzac104
Mueller, M. J., Tuttle, L. J., LeMaster, J. W., Strube, M. J., McGill, J. B., Hastings, M. K., & Sinacore, D. R. (2012). Weight-Bearing versus Nonweight-Bearing Exercise for persons with diabetes and peripheral neuropathy: a randomized controlled trial. Archives of Physical Medicine and Rehabilitation, 94(5), 829–838. https://doi.org/10.1016/j.apmr.2012.12.015

Akbari, N. J., & Naimi, S. S. (2022). The effect of exercise therapy on balance in patients with diabetic peripheral neuropathy: a systematic review. Journal of Diabetes & Metabolic Disorders, 21(2), 1861–1871. https://doi.org/10.1007/s40200-022-01077-1
Acknowledgements
We would like to express our sincere gratitude to the Department of Physiotherapy and Rehabilitation at Jashore University of Science and Technology (JUST) for partially funding this study. We also thank the faculty members, clinical staff, and all participants whose support and cooperation were essential to the successful execution of this research.