Sep 29, 2025

Public workspaceDual coloMOCA implantation protocol 

DOI
https://dx.doi.org/10.17504/protocols.io.36wgq3535lk5/v1
Dual coloMOCA implantation protocol
  • Brett Hanzlicek1,
  • Dennis Bourbeau2
  • 1Advanced Platform Technology Center, Louis Stokes VA Hospital, Cleveland, Ohio;
  • 2MetroHealth Medical Center, Cleveland, Ohio
Brett Hanzlicek
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DOI: https://dx.doi.org/10.17504/protocols.io.36wgq3535lk5/v1
Protocol Citation: Brett Hanzlicek, Dennis Bourbeau 2025. Dual coloMOCA implantation protocol . protocols.io https://dx.doi.org/10.17504/protocols.io.36wgq3535lk5/v1
License: This is an open access protocol distributed under the terms of the Creative Commons Attribution License,  which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited
Protocol status: Working
We use this protocol and it's working
Created: June 29, 2023
Last Modified: September 29, 2025
Protocol Integer ID: 84242
Keywords: colomoca implantation protocol, dual colomoca implantation protocol, colomoca, bowel device, implantation, pig, protocol
Abstract
This protocol describes the implantation of two bowel devices (ColoMOCA) in pigs.
Troubleshooting
Anesthesia
Anesthetize/prep the animal for surgery.

Aseptic procedures by trained personnel are utilized during the surgery. All tools are sterilized prior to insertion. Drapes will be used and personnel performing surgery will wear clean surgical scrubs, and sterile gowns/gloves and masks.
Laparotomy
Make a midline suprapubic incision ~9 cm long to expose the peritoneal cavity and viscera.
Colotomy
Make two small incision into the colon.
Insert and anchor ColoMOCA
Insert devices through the small incision and secure in place with sterile non-absorbable sutures.
Test Wireless Transmission
Wake the coloMOCAs with radio if not already awake. Confirm data transmission.
Close incision
  • Close the colon with an absorbable suture in an interrupted pattern
  • Close the peritoneum and fascia with absorbable sutures using a continuous suture pattern.
  • Close the subcutaneous tissue and skin with non-absorbable monofilament suture with a cutting needle, using an interrupted suture pattern. Skin staples may also be used.
Test Wireless Transmission (2)
Confirm data transmission and then put devices to sleep
CT-Imaging
Image to verify placement of the sensors.
Place jacket on the pig
Place and zip the jacket on the pig while still anesthetized.
Wake up the animal
Stay with the animal until fully awake. Return to pig room.