Oct 14, 2021

Public workspaceDonor Acceptance Criteria for TMC Florida/Zurich HuBMAP Inclusion V.2

DOI
dx.doi.org/10.17504/protocols.io.bsdsna6e
  • 1University of Florida
  • Human BioMolecular Atlas Program (HuBMAP) Method Development Community
    Tech. support email: Jeff.spraggins@vanderbilt.edu
Marda Jorgensen
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DOI: dx.doi.org/10.17504/protocols.io.bsdsna6e
Protocol Citation: Marda Jorgensen, Clive Wasserfall 2021. Donor Acceptance Criteria for TMC Florida/Zurich HuBMAP Inclusion. protocols.io https://dx.doi.org/10.17504/protocols.io.bsdsna6eVersion created by Marda Jorgensen
License: This is an open access protocol distributed under the terms of the Creative Commons Attribution License,  which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited
Protocol status: Working
We use this protocol and it’s working
Created: February 13, 2021
Last Modified: October 14, 2021
Protocol Integer ID: 47250
Abstract
This document outlines the required criteria for inclusion for donors of thymus, lymph nodes and spleen in the HuBMAP project.
Donor Criteria
Donor Criteria
A copy of the complete recovery checklist must be provided
BMI must be in keeping with CDC published growth charts 5th to 95th percentile
Donor must be less than seven days on ventilator

Donor tissue must be received within 24 hours of recovery

Contraindications for donor acceptance are
More than 4 blood transfusions
Any autoimmune diseases
Chromosomal abnormalities
Bacterial or viral meningitis or MRSA in any culture
Donor Criteria
Donor Criteria
Sepsis
Observable infarction, rupture, deflation or gross abnormality
Donor Criteria
Donor Criteria
Immune deficiency diseases
Cancer
Any active known infections including SARS-Cov-2
Spleen Specific Criterion
Spleen Specific Criterion
Must receive at least 50% of the intact spleen, including hilum.
Spleen Specific Criterion
Spleen Specific Criterion
No spenomegly
Lymph Node Specifc Criterion
Lymph Node Specifc Criterion
Must receive at least 4 intact lymph nodes
Thymus Specific Criterion
Thymus Specific Criterion
Must be under the age of 50 to permit for adequate lymphoid tissue presence