Data sources: Pubmed, Cochrane, Web of Science, Science Direct, Scopus, and Ovid MD. Searched until 30th April 2017. (chlorhexidine) AND (bacteremia OR bacteraemia) AND (extraction OR removal) were used as key words in a free-text search. Meeting Abstracts published were searched. References of each article were reviewed. We only included randomized controlled clinical trials. There were no restrictions regarding language or date of publication. The outcome measure was set on the incidence of the bacteremia measure within the first ten minutes post-extraction. Two reviewers independently undertook the risk of bias assessment and data extraction. A fixed-effect inverse variance weighted meta-analysis was conducted.