Oct 02, 2021
Continuous positive airway pressure to reduce the risk of early peripheral oxygen desaturation following apnoea onset in children: Randomised double-blind controlled trial
- 1Universidade Federal de Pernambuco
External link: https://doi.org/10.1371/journal.pone.0256950
Protocol Citation: Jayme Marques 2021. Continuous positive airway pressure to reduce the risk of early peripheral oxygen desaturation following apnoea onset in children: Randomised double-blind controlled trial. protocols.io https://dx.doi.org/10.17504/protocols.io.bqv5mw86
Manuscript citation:
Neto JMdS, Carvalho CCd, Andrade LBd, Santos TGBD, Andrade RGAdC, Fernandes RAML, Orange FAd (2021) Continuous positive airway pressure to reduce the risk of early peripheral oxygen desaturation after onset of apnoea in children: A double-blind randomised controlled trial. PLoS ONE 16(10): e0256950. doi: 10.1371/journal.pone.0256950
License: This is an open access protocol distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited
Protocol status: Working
Created: December 18, 2020
Last Modified: October 02, 2021
Protocol Integer ID: 45725
Keywords: continuous positive airway pressure;, general anaesthesia, hypoxia, noninvasive ventilation, patient safety, paediatrics,
Abstract
It was a randomised double-blind parallel controlled clinical trial, in a tertiary teaching hospital with 68 children, aging 2-6 years, ASA I-II, who presented for surgery under general anaesthesia, divided into two groups of 34 participants (CPAP and controls). The intervention was CPAP-ventilation and passive CPAP-oxygenation using the anaesthesia workstation. The main outcome measure was the occurrence of a SpO2 of 95% during a follow-up period of 300 seconds from the beginning of the apnoea. We alternatively registered the time from the onset of apnoea until a SpO2 of 95% (limited to 300 seconds) – with SpO2 recorded each 30 seconds - (T1) and time from a SpO2 of 95% to previous baseline levels aided by positive pressure ventilation (T2).0 µL
Attachments
Continuous positive airway pressure to reduce the risk of early peripheral oxygen desaturation following apnoea onset in children: Randomised double-blind controlled trial
Continuous positive airway pressure to reduce the risk of early peripheral oxygen desaturation following apnoea onset in children: Randomised double-blind controlled trial
Continuous positive airway pressure to reduce the risk of early peripheral oxygen desaturation following apnoea onset in children: Randomised double-blind controlled trial