Feb 05, 2020

Public workspaceComparative Efficacy of Antidepressants for Symptoms Remission of Gastroesophageal Reflux: A Bayesian Network Meta-Analysis of Randomized Controlled Trails (protocol) V.3

DOI
dx.doi.org/10.17504/protocols.io.bb72irqe
  • Xiaobei Si1,
  • Deying Bi1,
  • Linyu Huo2,
  • Yu Lan1,
  • Shuo Zhang3
  • 1Beijing Jishuitan Hospital;
  • 2Beijing Haidian Hospital;
  • 3Fu Wai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences
Xiaobei Si
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DOI: dx.doi.org/10.17504/protocols.io.bb72irqe
Protocol Citation: Xiaobei Si, Deying Bi, Linyu Huo, Yu Lan, Shuo Zhang 2020. Comparative Efficacy of Antidepressants for Symptoms Remission of Gastroesophageal Reflux: A Bayesian Network Meta-Analysis of Randomized Controlled Trails (protocol). protocols.io https://dx.doi.org/10.17504/protocols.io.bb72irqe
Manuscript citation:

License: This is an open access protocol distributed under the terms of the Creative Commons Attribution License,  which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited
Protocol status: Working
We use this protocol and it's working
Created: February 05, 2020
Last Modified: February 05, 2020
Protocol Integer ID: 32730
Keywords: antidepressants; gastro-esophageal reflux; network meta-analysis,
Abstract
Objective The aim of this study is to compare symptom relieving of antidepressants for gastroesophageal reflux.
Methods We plan to include randomized controlled trials (RCTs) that evaluate efficacy of antidepressants for gastroesophageal reflux by searching the MEDLINE, EMBASE, Web of Science, China National Knowledge Infrastructure Database (CNKI), Chinese VIP Information (VIP), Chinese Medical Databases (CMB) and Wan-Fang databases from the starting date of database establishment till September 31, 2019. The words of "gastroesophageal reflux disease", "antidepressant" and their synonyms will be adopted as searching terms. ADDIS 1.16.8 will be used for network meta-analysis, with conduction of node split analysis as well as rank probability analysis.
Conclusions The present analysis aims to further compare efficacy of symptom relieving of gastroesophageal reflux among antidepressants, which apply clinical evidence for further therapy of gastroesophageal reflux diseases.
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