Behavior Working Group Suggested Protocols

Eileen Ruth Torres; Alexandra Nelson; Per Svenningsson; Thomas Wichmann; Roberta Marongiu

Apr 22, 2025

Version 1

Behavior Working Group Suggested Protocols V.1

DOI

dx.doi.org/10.17504/protocols.io.n2bvjnze5gk5/v1

Eileen Ruth Torres^1,2,
Alexandra Nelson^3,4,5,2,
Per Svenningsson^6,2,
Thomas Wichmann^7,8,9,2,
Roberta Marongiu^1,2

¹Department of Neurological Surgery, Weill Cornell Medical College, New York, NY 10065;
²Aligning Science Across Parkinson’s (ASAP) Collaborative Research Network, Chevy Chase, MD 20815, USA;
³Kavli Institute for Fundamental Neuroscience, UCSF, San Francisco, CA 94158, USA;
⁴Weill Institute for Neurosciences, UCSF, San Francisco, CA 94158, USA;
⁵Department of Neurology, UCSF, San Francisco, CA 94158, USA;
⁶Department of Clinical Neuroscience, Karolinska Institutet, 171 76 Stockholm, Sweden;
⁷Department of Neurology, School of Medicine, Emory University, Atlanta, GA 30329, USA;
⁸Udall Center of Excellence in Parkinson’s Disease Research, Emory University, Atlanta, GA 30329, USA;
⁹Emory National Primate Research Center, Emory University, Atlanta, GA 30329, USA

Jacquelyn Haytayan

Weill Cornell Medicine

DOI: dx.doi.org/10.17504/protocols.io.n2bvjnze5gk5/v1

Collection Citation: Eileen Ruth Torres, Alexandra Nelson, Per Svenningsson, Thomas Wichmann, Roberta Marongiu 2025. Behavior Working Group Suggested Protocols. protocols.io https://dx.doi.org/10.17504/protocols.io.n2bvjnze5gk5/v1

License: This is an open access collection distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited

Protocol status: Working

We use this collection and it's working

Created: July 25, 2024

Last Modified: May 05, 2025

Collection Integer ID: 104087

Keywords: ASAPCRN, behavior, motor symptoms, non-motor symptoms, animal models

Funders Acknowledgements:

Aligning Science Across Parkinson's

Grant ID: 020608

Aligning Science Across Parkinson's

Grant ID: 020529

Aligning Science Across Parkinson's

Grant ID: 020572

Abstract

This collection of rodent behavioral assays from the ASAP Workspace are examples of detailed protocols that may be used for testing motor and/or non-motor symptoms of Parkinson's disease. 

We include considerations in the guidelines attached in order to help ensure that a relevant test is chosen based on the symptom ones wishes to model, testing conditions are appropriate, and confounding factors are reduced as much as possible. Appropriate control groups should always be included in tested, and groups should be counterbalanced.

Attachments